Multiple Micronutrient Supplements (MMS) Technical Specification

Multiple micronutrient supplements (MMS) are proven to drive better birth outcomes than iron-folic acid (IFA) alone. What follows is guidance to inform program developers as they conceptualize how to introduce MMS and equip manufacturers (both local and global) to produce MMS at international quality standards.

Guidance to Governments, Program Developers, and Manufacturers

As governments, NGOs, and other partners look to transition from IFA to MMS, there are several decision points to navigate, from formula through packaging. 

Recommended Specifications

At Kirk Humanitarian, we manufacture MMS consistent with the United Nations International Multiple Micronutrient Antenatal Preparation (UNIMMAP) formula, manufactured to international quality standards (under a Stringent Regulatory Authority). 

Kirk Humanitarian’s UNIMMAP MMS tablets are categorized under the U.S. Food and Drug Administration (USFDA) regulations as a dietary supplement, delivered in a high-density polyethylene (HDPE) 180-count, tamperevident, and childresistant bottle with a 1-gram desiccant pack and carrying a 30-month expiration label claim under Zone IVB climatic and humidity conditions. This format of UNIMMAP MMS, as delivered by Kirk Humanitarian, currently is the recommended, default format and will continue to be unless research shows alternative packaging (e.g., blister packs or a smaller bottle) can improve uptake and adherence of MMS by pregnant women. 

This format of UNIMMAP MMS is designed to reduce accidental use by children, reduce environmental waste, and reduce overall product cost for health care systems. 

Our MMS Labeling, Packaging, and Supplementary Materials

Label Information

  • USP designation of UNIMMAP MMS Product delivered by KH: oil- and water-soluble vitamins with minerals tablets 
  • USP verification mark in progress 
  • 30-month shelf life 
  • Zone IVB climatic conditions 
  • Dietary Supplement Panel 

Bottle

  • Tablets per bottle: 180 
  • Weight: 109 g 
  • Expiration: 30 months 
  • UV-resistant bottle 
  • Opaque (HDPE) material 
  • Tamper-evident 
  • Childresistant 
  • Desiccant (1gram packet) 

Box

Pallet

  • Weight: 346 kg
  • Boxes per pallet: 30
  • Dimensions: 48” x 40” x 43.625”
Instructional Insert

A product usage and informational sheet for those distributing UNIMMAP MMS to pregnant women is included in each pallet and is intended to summarize the appropriate information that should be communicated to recipients of UNIMMAP MMS.

[MMS] is just one part of ensuring a positive pregnancy experience and healthy growth and development for all infantsBut it’s something that can be done right now as policymakers and health care providers strive for the best outcomes for women and children.

Emily Smith, Harvard T.H. Chan School of Public Health 

Learn more about our work.

Further explore the research on MMS.